Ursolic acid is a pentacyclic triterpenoid. Ursolic acid is present in many plants, including apples, bilberries, cranberries, elder flower, peppermint, lavender, oregano, thyme, hawthorn, prunes. Ursolic acid has medicinally action, both topically and internally. Ursolic acid is used in many cosmetic preparations for its anti-inflammatory, antitumor and antimicrobial properties. Ursolic acid has antibacterial and antifungal activity. Tests have shown that Ursolic acid inhibits the growth of Candida albicans and Microsporium lenosum. Ursolic acid has anti-inflammatory properties and is used in ointments to treat burns. Topical application of ursolic acid inhibited TPA-induced initiation and promotion of tumor growth.
Ursolic acid is one of the most frequently found natural plant triterpenic acids – metabolite of herbaceous and fruticose plants such as cowberry, whortleberry, cranberry, sea-buckthorn, bearberry, hawthorn, dog-rose, rhododendron, etc., that are used in folk medicine. Ursolic acid and its native compositions are used in pharmacology (one can find more than 1,500 sources in scientific literature) predominantly as a component of preventive medicine for various diseases including lymphocytic leucaemia, neoplastic tumors, and as a modifier of protein synthesis. |